In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells.
Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University of Zurich has succeeded in sustainably lowering high LDL cholesterol levels in the blood of mice and macaques. This opens up the possibility of curing patients with inherited metabolic liver diseases.
Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.
Researchers from North Carolina State University have developed a fundamentally new approach to DNA data storage systems, giving users the ability to read or modify data files without destroying them and making the systems easier to scale up for practical use.
Scientists computed a zoo of millions of alternate genetic polymer molecular structures, giving context for why biology encodes information how it does, and providing potential leads for new drugs and a guide to searches for extraterrestrial biology.