Intracellular signaling pathways regulating Са2+ homeostasis

Place of work — Mayo
Clinic, USA
Contacts — 200 1st Street South West Rochester, MN 55905, USA (507) 255–5123 Chini.eduardo@mayo.edu
Publications — Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38. Aksoy P, Escande C, White TA, hompson M, Soares S, Benech JC, Chini EN. Biochem Biophys Res Commun. 2006 Oct 13;349(1):353–9.
CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions. Chini EN. Curr Pharm Des. 2009;15(1):57–63.
NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. Soares S, тThompson M, White T, Isbell A, Yamasaki M, Prakash Y, Lund FE, Galione A, Chini EN. Am J Physiol Cell Physiol. 2007 Jan;292(1):C227-39.