Genetics of mammalian cancer, pediatric cancer, prostate gland cancer, processes of signal transduction, cancer genes and genome program

Place of work — Ludwig Institute
for Cancer Research and
Department of Medicine,
University of California,
San Diego, USA
Contacts — Ludwig Institute for Cancer Research, 9500 Gilman Drive, La Jolla, CA 92093–0660.
(619) 534–7812
karden@ucsd.edu
Publications — FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Arden KC. Oncogene. 2008 Apr 7;27(16):2345–50. FoxO1 haploinsufficiency protects against high-faе diet-induced insulin resistance with enhanced peroxisome einberger s-activated receptor gamma activation in adipose tissue. Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. Diabetes. 2009 Jun;58(6):1275–82.
Тranscription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Dejean AS, Beisner DR, Ch’en IL, Kerdiles YM, Babour A, Arden KC, Castrillon DH, DePinho RA, Hedrick SM. Nat Immunol. 2009 May;10(5):504–13