A topical nutritionally balanced and bioactive composition is provided to expeditiously intercede in the biological process of pre-mature solar aging of skin. An ingredient, which re-vitalizes senescent adult human dermal stem cells, has been integrated in the composition. The efficacious bioavailability of this anti-aging composition is assured by means of a bi-functional chemical penetration enhancing compound, which is integrated in this comprehensive formulation. The bi-functional chemical penetration enhancing compound for hosting other guest molecules to facilitate their expeditious bio-availability is presented.