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Radiation genetics

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Effect of low-dose radiation studied in the Drosophila melanogaster model system

A. Moskalev’s team carries out investigation in the field of radiation genetics and gerontology. A. Moskalev’s team has studied an adaptive response (changes in the life span) to low-dose radiation in Drosophila melanogaster. One of the wild type lines of D. melanogaster, together with mutant lines having mutations in the heat shock factor (Hsf) genes and in the heat shock protein genes, were used in the experiments. Scientists have shown that the radiation stress has no stimulatory effect on the life spans of the flies with mutated Hsp and Hsf genes, i.e. it does not cause the adaptive response. Research results indicate that induction of heat shock proteins is one of the primary protective mechanisms under stress conditions.