A. Asea’s department studies hsp activity aiming to develop effective immunotherapeutic approaches using those proteins. This group have found for the first time that exogenous hsp70 has high cytokine activity. The scientists established that widely used adaptogens can affect plasmatic level of hsp. It was shown in experiments on mice that being regularly used, extracts of Siberian ginseng (Eleutherococcus senticosus), snowdon rose (Rhodiola rosea) and magnolia vine (Schisandra chinensis) lead to increase of the plasmatic level of hsp72. Thus an organism interprets taking adaptogens as a peculiar stress, and the resistance of the organism to actual stress situations increases. The scientists have also evaluated the role of hsp in longevity. They supposed that the level of hsp70
Place of work - Proteomics Core
Facility Scott & White
Hospital,USA
Contacts - Scott & White Hospital
2401 S. 31st St.
Temple, TX 76508
(254) 743–0201
asea@medicine.tamhsc.edu
aasea@swmail.sw.org
Publications - Adaptogens exert a
Panossian A, Wikman G, Kaur P, Asea A. Phytomedicine. 2009 Jun;16(6–7):617–22. Serum heat shock protein 70 level as a biomarker of exceptional longevity. Terry DF, Wyszynski DF, Nolan VG, Atzmon G, Schoenhofen EA, Pennington JY, Andersen SL, Wilcox MA, Farrer LA, Barzilai N, Baldwin CT, Asea A. Mech Ageing Dev. 2006 Nov;127(11):862–8. Hsp70: a chaperokine. Asea A. Novartis Found Symp. 2008;291:173–179.