The study by San
Genentech’s Colombian trial involves approximately 300 people, with about 200 being suspected of carrying the rare gene. Half of those 200 will receive the
In the Colombia trial, researchers told the Journal they can deliver better results by starting treatment earlier -«before the onset of symptoms and severe damage to the brain in people who would otherwise be certain to get the disease.»
Following Biogen’ successful data, Roche researchers said they were more confident in their drugs targeting the plaque. They said they would take another look at two experimental drugs that suffered setbacks in2014. Last the company said gantenerumab was not proving effective. Likewise, Roche (RHHBY) reported in July that renezumab, another Alzheimer’s drug in clinical trials, failed to help people with mild to moderate Alzheimer’s.
There are several drugs on the market that help manage Alzheimer’s, but none treat the primary cause. According to a Bloomberg report, there have been more than 100 failed efforts to develop a treatment for Alzheimer’s disease since 1998. In addition to Roche’s two failed drugs, pharmaceutical giants Eli Lilly and Company (LLY) and Pfizer Inc. (PFE) have also reported setbacks with their experimental Alzheimer’s treatments. Eli Lilly does have another experimental drug in Phase III trials with results expected sometime in 2016. Lilly’s solanezumab targets the amyloid plaque.
By Alex Keown, BioSpace.com Breaking News Staff